Eccrine Angiomatous Hamartoma in a Patient with Nevus Depigmentosus and Nevus Spilus

A 3-year-old boy visited the Department of Plastic Surgery of our hospital, complaining of a painful nodule on the hand which had existed since birth. Physical examination revealed a skin-colored, smooth, small nodule on the left thumb [Figure 1a]. Neither palmar hyperhidrosis nor finger hyperplasia was observed. In addition, the patient had a depigmented macule on the left abdomen [Figure 1b] and a pigmented freckle on the right upper extremity [Figure 1c], both of which were developed soon after birth. All the skin lesions were considered benign; however, according to the parents’ wish, the digital nodule was completely resected and biopsy was performed from the depigmented macule under general anesthesia. Histological examination showed nodular clusters composed of eccrine glands and dilated vessels in the lower dermis [Figure 2a]. Immunohistochemistry showed a number of CD31-positive vessels within the foci of eccrine sweat glands [Figure 2b]. A biopsy specimen from the depigmented macule showed no specific features. Unfortunately, histological examination was not carried out on the nevus spilus on the arm. The patient has been followed up without local recurrence.